CDC42_HUMAN_1_184

Cell division control protein 42 homolog [Small GTPase superfamily. Rho family. CDC42 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CDC42_HUMAN):12:18,28,32:35,60,61,116,118,119,158:16012:18,28,32:35,60,61,116,118,119,158:160
Metals (Me):Mg

Full PDB list

1a4r,1am4,1an0,1doa,1grn,1gzs,1ki1,1kz7,1kzg,1nf3,2dfk,2ngr,2odb,2qrz,2wm9,2wmn,2wmo,3eg5,3gcg,3qbv,3vhl,4did,4itr,4js0,4yc7,5c2j,5cjp,5fi1 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 Me
G
1
2
A
1
3
V
1
4
G
1
5
K
1
6
T
1
7
C
1
8
F
2
8
Y
3
2
V
3
3
P
3
4
T
3
5
G
6
0
Q
6
1
Q
1
1
6
D
1
1
8
L
1
1
9
S
1
5
8
A
1
5
9
L
1
6
0
[1]1a4r.a gdp 28 V . . . . . . . . . . . . . . . . . . . Mg
[1]1a4r.b gnh 28 V . . . . . . . . . . . . . . . . . . .
[1]4itr.c gdp 28 . . . . . . . . . . . . . . . . . . . . Mg
[1]1am4.d gnp 32 . . . . . . . . . . . . . . . . . . . . Mg
[1]1grn.a al,gdp 29 . . . . . . . . . . . . . . . . . . . . Mg
[1]4did.a gdp 28 . . . . . . . . . . . . . . . . . . . . Mg
[1]1nf3.a gnp 32 . . . . . . . . . . . . . L . . . . . . Mg
[1]2dfk.b none . . . . . . . . . . . . . . . . . . . .
[1]2odb.a gcp 32 . . . . . . . . . . . . . . . . . . . . Mg
[1]2wmo.b gtp,mg 33 . . . . . . . . . . . . . . . . . . . .
[1]3vhl.b none . . . . . N . . . . . . . . . . . . . .
[1]4js0.a gnp 32 V . . . . . . . . . . . . . . . . . . . Mg
[1]4yc7.a gnp,mg 33 . . . . . . . . . . . . . . . . . . . .
[1]5cjp.b gtp 32 . . . . . . . . . . . . . L . . . . . . Mg

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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