CBR1_HUMAN_2_277

Carbonyl reductase [NADPH] 1 [Short-chain dehydrogenases/reductases (SDR) family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CBR1_HUMAN):R: Glutathione binding (95:97)
R: Glutathione binding (193,194)
94,103,106,140:142,145,192,227,229,230,235,236
94:97,103,106,140:142,145,192:194,227,229,230,235,236
Cofactors (cF):nap/ndp

Full PDB list

1wma,2pfg,3bhi,3bhj,3bhm,4z3d

Contact map

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ligand
A1 cF
A
9
4
F
9
5
K
9
6
V
9
7
F
1
0
3
Q
1
0
6
S
1
4
0
I
1
4
1
M
1
4
2
R
1
4
5
S
1
9
2
A
1
9
3
Y
1
9
4
C
2
2
7
G
2
2
9
W
2
3
0
M
2
3
5
A
2
3
6
[1]2pfg.a ddd 22 . . . . . . . . . . . . . . . . . . nap
[1]1wma.a ab3,pe5 48 . . . . . . . . . . . . . . . . . . ndp
[1]3bhm.a ab3,ahe 43 . . . . . . . . . . . . . . . . . . nap
[1]3bhi.a none . . . . . . . . . . . . . . . . . . nap
[1]3bhj.a ab3,gsh 41 . . . . . . . . . . . . . . . . . . nap
[1]4z3d.b gsh 20 . . . . . . . . . . . . . . . . . . ndp

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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