CATD_HUMAN_63_411

Cathepsin D [Peptidase A1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CATD_HUMAN):D: Peptidase A1 (95,97,99,100,141:144,189,190,192,193,195,198,206,269,293,295,297:299,324,373,375,376,379,384)
77,78
77,78,95,97,99,100,141:144,189,190,192,193,195,198,206,269,293,295,297:299,324,373,375,376,379,384

Full PDB list

1lya,1lyb,1lyw,4obz,4oc6,4od9 (redundant pocketome entry)

Contact map

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ligand
A1
A
7
7
Q
7
8
V
9
5
D
9
7
G
9
9
S
1
0
0
H
1
4
1
Y
1
4
2
G
1
4
3
S
1
4
4
T
1
8
9
F
1
9
0
A
1
9
2
A
1
9
3
F
1
9
5
I
1
9
8
I
2
0
6
Y
2
6
9
I
2
9
3
D
2
9
5
G
2
9
7
T
2
9
8
S
2
9
9
E
3
2
4
M
3
7
3
I
3
7
5
P
3
7
6
S
3
7
9
I
3
8
4
[1]4obz.a 2s4 25 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4od9.a 2rz 39 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1lya.c none . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1lyb.a ivaVVstaAsta 48 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4oc6.a 2s1 58 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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