CATB_HUMAN_127_335

Cathepsin B [Peptidase C1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CATB_HUMAN):101:109,147,148,151:155,187:190,198:200,252,255,275:279,300,324101:109,147,148,151:155,187:190,198:200,252,255,275:279,300,324

Full PDB list

1csb,1gmy,1huc,1pbh,2ipp,2pbh,3ai8,3cbj,3cbk,3k9m,3pbh (redundant pocketome entry)

Contact map

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ligand
A1
D
1
0
1
Q
1
0
2
G
1
0
3
S
1
0
4
C
1
0
5
G
1
0
6
S
1
0
7
C
1
0
8
W
1
0
9
G
1
4
7
D
1
4
8
N
1
5
1
G
1
5
2
G
1
5
3
Y
1
5
4
P
1
5
5
C
1
8
7
E
1
8
8
H
1
8
9
H
1
9
0
C
1
9
8
T
1
9
9
G
2
0
0
A
2
5
2
V
2
5
5
M
2
7
5
G
2
7
6
G
2
7
7
H
2
7
8
A
2
7
9
W
3
0
0
E
3
2
4
[1]1csb.a ep0 26 . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . .
[1]1gmy.a aem.apd.dfa 31 . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . .
[1]3ai8.b hnq 14 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]2ipp.a pys 7 . . . . . . . * . . . . . . . . . . . . . . . . . . . . . . . .
[2]2pbh.a none . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3cbj.a TTG-SKLLG 53 . . . . . . . A . . . . . . . . . . A . . . . . . . . . . . . .
[1]3cbk.a TTG-KLLG 47 . . . . . . . A . . . . . . . . . . A . . . . . . . . . . . . .
[1]3k9m.b IPG-VVAG 42 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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