CASP1_HUMAN_121_404

Caspase-1 [Peptidase C14A family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (CASP1_HUMAN):177,179,236:238,283:285177,179,236:238,283:285

Full PDB list

1bmq,1ibc,1ice,1rwk,1rwm,1rwn,1rwo,1rwp,1rwv,1rww,1rwx,1sc1,1sc3,1sc4,2fqq,2h48,2h4w,2h4y,2h51,2h54,2hbq,2hbr,2hby,2hbz,3d6f,3d6h,3d6m,3e4c,3ns7 (redundant pocketome entry)

Contact map

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ligand
A1
P
1
7
7
R
1
7
9
S
2
3
6
H
2
3
7
G
2
3
8
Q
2
8
3
A
2
8
4
C
2
8
5
[1]1rwp.a hqc 34 . . . . . . . *
[1]1rwv.a 5ph 36 . . . . . . . *
[1]1rwn.a 4qb 37 . . . . . . . *
[1]1rww.a oqb 37 . . . . . . . *
[1]1bmq.a mno 38 . . . . . . . *
[1]1rwm.a q2y 37 . . . . . . . *
[1]1rwx.a ybh 40 . . . . . . . *
[1]1rwo.a bth 41 . . . . . . . *
[1]1rwk.a 158 13 . . . . . . . *
[1]1ibc.a aceWEHasa 44 . . . . . . . .
[1]1ice.a aceYVAasa 35 . . . . . . . *
[1]1sc3.a mli 7 . . . . . . . A
[1]2h4y.a phqVADcf0 31 . . . . . . . *
[1]2h54.a phqVADcf0 31 . . . . . . . *
[1]2hbz.a phqVADcf0 31 . . . . . . . *
[2]3e4c.a none . . . . . . . A
[1]3ns7.a 3ns 30 . . . . . . . *

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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