CAN1_RAT_24_356

Calpain-1 catalytic subunit [Peptidase C2 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CAN1_RAT):D: Calpain catalytic (72,109,110,112:116,206:210,212,251:253,260,261,271:273,298,300,347)72,109,110,112:116,206:210,212,251:253,260,261,271:273,298,300,347
Metals (Me):Ca

Full PDB list

1kxr,1tl9,1tlo,2g8e,2g8j,2nqg,2nqi,2r9c,2r9f1qxp (unprocessed)

Contact map

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ligand
A1 Me
E
7
2
Q
1
0
9
G
1
1
0
L
1
1
2
G
1
1
3
D
1
1
4
C
1
1
5
W
1
1
6
S
2
0
6
G
2
0
7
G
2
0
8
C
2
0
9
T
2
1
0
E
2
1
2
S
2
5
1
I
2
5
2
N
2
5
3
L
2
6
0
E
2
6
1
G
2
7
1
H
2
7
2
A
2
7
3
W
2
9
8
E
3
0
0
K
3
4
7
[1]2g8e.a 0m6 24 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]1tlo.a e64 25 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]2r9f.a k2z 37 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]2r9c.a grd 40 . . . . . . . . . . . . . . . . . . . . . . . . . Ca
[1]2g8j.a d7g 35 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]2nqi.a nqi 43 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]2nqg.a nqg 44 . . . . . . * . . . . . . . . . . . . . . . . . . Ca
[1]1kxr.a none . . . . . . S . . . . . . . . . . . . . . . . . . Ca
[1]1tl9.a aceLLar7 30 . . . . . . . . . . . . . . . . . . . . . . . . . Ca

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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