CAH1_HUMAN_2_261

Carbonic anhydrase 1 [Alpha-carbonic anhydrase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (CAH1_HUMAN):D: Alpha-carbonic anhydrase (63,65,66,68,70,92,93,95,97,120,122,132,133,136,142,144,199:203,210)
R: Substrate binding (200,201)
63,65,66,68,70,92,93,95,97,120,122,132,133,136,142,144,199:203,210
Metals (Me):Hg/Zn

Full PDB list

1azm,1bzm,1crm,1czm,1hcb,1hug,1huh,1j9w,1jv0,2cab,2foy,2fw4,2it4,2nmx,2nn1,2nn7,3lxe,3w6h,3w6i,4wr7,4wup,4wuq,5e2m (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
V
6
3
H
6
5
S
6
6
H
6
8
N
7
0
F
9
2
Q
9
3
H
9
5
H
9
7
H
1
2
0
A
1
2
2
L
1
3
2
A
1
3
3
A
1
3
6
L
1
4
2
V
1
4
4
L
1
9
9
T
2
0
0
H
2
0
1
P
2
0
2
P
2
0
3
W
2
1
0
[1]3lxe.a tor 22 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]4wuq.a 3ug 20 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]5e2m.b v14 28 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3w6h.a azm,flb 33 . . . * . . . . . . . . . . . . . . . . . . Zn
[1]4wr7.b 3tv 18 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2nn7.b m29 17 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2nmx.b m25 16 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]4wup.b 3uf 14 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2nn1.b m28 15 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1bzm.a mzm 14 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1azm.a azm 13 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1crm.a none . . . . . . . . . . . . . . . . . . . . . . Hg
[1]3w6i.a flb 20 . . . * . . . . . . . . . . . . . . . . . . Zn
[1]1czm.a aas 11 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1hug.a au,auc,auc 6 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1j9w.b none . . . R . . . . . . . . . . . . . . . . . . Zn
[1]1jv0.b zn 1 . . . R . . . . . . . . . . . . . . . . . . Zn
[1]2cab.a none . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2foy.b b30 25 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2fw4.a H 11 . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2it4.a ppf 7 . . . . . . . . . . . . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback