C1TC_HUMAN_1_305

C-1-tetrahydrofolate synthase, cytoplasmic

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (C1TC_HUMAN):R: Methylenetetrahydrofolate dehydrogenase and cyclohydrolase (52,55,56,98:101,125,238,272,273,276,277,279,280)
R: Substrate binding (272,273,276)
52,55,56,98:101,125,238,272,273,276,277,279,280
Cofactors (cF):nap/ndp

Full PDB list

1a4i,1dia,1dib,1dig

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 cF
Y
5
2
V
5
5
K
5
6
L
9
8
V
9
9
Q
1
0
0
L
1
0
1
D
1
2
5
I
2
3
8
P
2
7
2
G
2
7
3
G
2
7
6
P
2
7
7
T
2
7
9
V
2
8
0
[1]1dia.a l24 32 . . . . . . . . . . . . . . . nap
[1]1dib.a l34 34 . . . . . . . . . . . . . . . nap
[1]1dig.a l37 31 . . . . . . . . . . . . . . . nap
[1]1a4i.a none . . . . . . . . . . . . . . . ndp

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback