If you see this message after the page is completely loaded, then JavaScript is not supported or disabled in your browser. Please consider enabling JavaScript for this site.

BT3A1_HUMAN_29_143

Butyrophilin subfamily 3 member A1 [Immunoglobulin superfamily. BTN/MOG family]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (BT3A1_HUMAN):D: Ig-like V-type 1 (64:66, 73, 78, 127, 129, 134)64:66, 73, 78, 127, 129, 134

Full PDB list

4f80, 4f9l, 4jkw, 4k55 (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
E
6
4
L
6
5
K
6
6
V
7
8
Y
1
2
7
Q
1
2
9
Y
1
3
4
[1]4f9l.b none . . . . . . .
[1]4jkw.a ipe14 . . . . . . .
[1]4k55.a h6p15 . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1
E
6
4
L
6
5
K
6
6
R
7
3
V
7
8
Y
1
2
7
Q
1
2
9
Y
1
3
4
[1]4f9l.b . . . . . . . .
[1]4jkw.a . . . . . . . .
[1]4k55.a . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
4f9l.b is apo
4jkw.a:ipe
4k55.a:h6p
[1] 4f9l.b
-
0.1 0.4
[1] 4jkw.a -
0
0.2
[1] 4k55.a - 0
0.1
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
4f9l.b
4jkw.a
4k55.a
[1] 4f9l.b
0
.02 .03
[1] 4jkw.a .02
0
.01
[1] 4k55.a .03 .01
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 0.8 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
4f9l.b
4jkw.a
4k55.a
[1] 4f9l.b
0
0.6 0.8
[1] 4jkw.a 0.6
0
0.4
[1] 4k55.a 0.8 0.4
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.4 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
4f9l.b
4jkw.a
4k55.a
[1] 4f9l.b
0
2.7 2.2
[1] 4jkw.a 2.7
0
0.8
[1] 4k55.a 2.2 0.8
0
[Binding site full-atom RMSD matrix]







[show 3D visualization]

[ENTRY 2D visualization]

L C X E | Background Color: | Anaglyph Stereo:

loading...