BRD2_HUMAN_343_458

Bromodomain-containing protein 2

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (BRD2_HUMAN):D: Bromo 2 (370:372,374,376,381,383,386,425,428:430,433:435)
438
370:372,374,376,381,383,386,425,428:430,433:435,438

Full PDB list

2dvv,2e3k,3oni,4j1p,4mr5,4mr6,4qeu,4qev,4qew,4uyg,5bt5,5dfb,5dfc,5dfd,5dw1,5ek9,5hfq,5ibn,5ig6 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
W
3
7
0
P
3
7
1
F
3
7
2
K
3
7
4
V
3
7
6
L
3
8
1
L
3
8
3
Y
3
8
6
C
4
2
5
Y
4
2
8
N
4
2
9
P
4
3
0
H
4
3
3
D
4
3
4
V
4
3
5
M
4
3
8
[1]4qev.a 31o 30 . . . . . . A . . . . . . . . .
[1]4qew.a 31p 31 . . . . . . A . . . . . . . . .
[1]5dfd.a 59e 31 F . . . . . . . . . . . . . . .
[1]5ek9.a 5p4 26 . . . . . . . . . . . . . . . .
[1]5ig6.a 6b3 24 . . . . . . . . . . . . . . . .
[1]5dw1.a 5gd 31 . . . . . . . . . . . . . . . .
[1]4uyg.a 73b 31 . . . . . . . . . . . . . . . .
[1]5dfc.a eam 30 F . . . . . . . . . . . . . . .
[1]4j1p.a 1k0 27 . . . . . . . . . . . . . . . .
[1]3oni.a jq1 31 . . . . . . . . . . . . . . . .
[1]5bt5.a 2lo 36 . . . . . . . . . . . . . . . .
[1]2e3k.b GalyG 20 . . . . . . . . . . . . . . . .
[1]2e3k.c RGalyG 31 . . . . . . . . . . . . . . . .
[1]2e3k.d RGaly 21 . . . . . . . . . . . . . . . .
[1]4qeu.a none . . . . . . A . . . . . . . . .
[1]5dfb.a none F . . . . . . . . . . . . . . .
[1]5ibn.a none . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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