BHMT1_HUMAN_1_406

Betaine--homocysteine S-methyltransferase 1

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (BHMT1_HUMAN):D: Hcy-binding (27:30,44,72,76,77,159,160,217,262,267,299,300)27:30,44,72,76,77,159,160,217,262,267,299,300
 • A2 (BHMT1_HUMAN):338338
Metals (Me):Zn

Full PDB list

1lt7,1lt8,1umy,4m3p (redundant pocketome entry)

Contact map

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ligand
A1 A2 Me
G
2
7
G
2
8
F
2
9
V
3
0
W
4
4
Q
7
2
F
7
6
Y
7
7
E
1
5
9
Y
1
6
0
C
2
1
7
I
2
6
2
F
2
6
7
C
2
9
9
C
3
0
0
H
3
3
8
[1]1lt8.a cbh 15 . . . . . . . . . . . . . . . . Zn
[1]1umy.d none . . . . . . . . . . . . . . . . Zn
[1]4m3p.a hcs 8 . . . . . . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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