BCL2_HUMAN_2_207

Apoptosis regulator Bcl-2 [Bcl-2 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (BCL2_HUMAN):99,100,103,104,107,108,110:112,115,118,119,129,132,133,136,137,139,140,143:146,148,149,152,153,156,198,201:203,20599,100,103,104,107,108,110:112,115,118,119,129,132,133,136,137,139,140,143:146,148,149,152,153,156,198,201:203,205

Full PDB list

2w3l,2xa0,4aq3,4ieh,4lvt,4lxd,4man,5agw,5agx,5jsn (redundant pocketome entry)

Contact map

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ligand
A1
Q
9
9
A
1
0
0
D
1
0
3
F
1
0
4
R
1
0
7
Y
1
0
8
R
1
1
0
D
1
1
1
F
1
1
2
M
1
1
5
Q
1
1
8
L
1
1
9
R
1
2
9
T
1
3
2
V
1
3
3
E
1
3
6
L
1
3
7
R
1
3
9
D
1
4
0
N
1
4
3
W
1
4
4
G
1
4
5
R
1
4
6
V
1
4
8
A
1
4
9
E
1
5
2
F
1
5
3
V
1
5
6
F
1
9
8
L
2
0
1
Y
2
0
2
G
2
0
3
S
2
0
5
[2]2w3l.a dro 42 E . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . .
[1]4lxd.a 1xv 48 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[2]2xa0.a LSECLRRIGDELDSNM 126 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
[3]4aq3.b 398,398 106 . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . -
[3]4aq3.c 398 53 . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]4ieh.a 1e9 59 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]4lvt.a 1xj 65 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[1]4man.a 1y1 65 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[5]5agx.a aceIxcpIAQajeLRmh8IGDmh8FNxcpYY 166 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . -
[4]5jsn.a D-AASLQANGDIFYAIL 118 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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