ARGI1_RAT_4_321

Arginase-1 [Arginase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ARGI1_RAT):R: Substrate binding (126,128,130)
R: Substrate binding (137,139)
101,124,135,141,142,183,186,232,234,246,277
101,124,126,128,130,135,137,139,141,142,183,186,232,234,246,277
Metals (Me):Mn

Full PDB list

1d3v,1hq5,1hqf,1hqg,1hqh,1hqx,1p8m,1p8n,1p8o,1p8p,1p8q,1p8r,1p8s,1r1o,1rla,1t4p,1t4r,1t4s,1t4t,1t5f,1t5g,1ta1,1tbh,1tbj,1tbl,1zpe,1zpg,2rla,3e8q,3e8z,3e9b,3rla,4rla,5rla (redundant pocketome entry)

Contact map

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ligand
A1 Me
H
1
0
1
D
1
2
4
H
1
2
6
D
1
2
8
N
1
3
0
T
1
3
5
S
1
3
7
N
1
3
9
H
1
4
1
G
1
4
2
D
1
8
3
E
1
8
6
D
2
3
2
D
2
3
4
T
2
4
6
E
2
7
7
[1]1r1o.a sdc 13 . . . . . . . . . . . . . . . . Mn
[1]1t5f.a dhh 12 . . . . . . . . A . . . . . . . Mn
[1]1d3v.a abh 13 . . . . . . . . . . . . . . . . Mn
[1]1hq5.a s2c 13 . . . . . . . . . . . . . . . . Mn
[1]1hqf.a har 13 . . . . . . . . . . . . . . . . Mn
[1]1hqg.a orn 9 . . . . . . . . * . . . . . . . Mn
[1]1hqh.a nnh 12 . . . . . . . . . . . . . . . . Mn
[1]1p8m.b none . . . E . . . . . . . . . . . . Mn
[1]1p8n.a none . . . . . . . . . . . . A . . . Mn
[1]1p8o.a none . . . N . . . . . . . . . . . . Mn
[1]1p8p.a none N . . . . . . . . . . . . . . . Mn
[1]1p8q.a none . . . . . . . . . . . . . E . . Mn
[1]1p8r.b s2c 13 E . . . . . . . . . . . . . . . Mn
[1]1p8s.b none . . . . . . . . . . . . C . . . Mn
[1]1rla.a none . . . . . . . . . . . . . . . . Mn
[1]1t4p.a 2bh 13 . . . . . . . . . . . . . . . . Mn
[1]1t4r.c ahi 9 . . . . . . . . . . . . . . . . Mn
[1]1t4s.a V 8 . . . . . . . . . . . . . . . . Mn
[1]1t4t.a dir 11 . . . . . . . . . . . . . . . . Mn
[1]1t5g.a R 12 . . . . . . . . A . . . . . . . Mn
[1]1ta1.a none . . . . . . . . C . . . . . . . Mn
[1]1tbh.a none . . . . . . . . D . . . . . . . Mn
[1]1tbj.a none . . . . . . . . A . . . . . . . Mn
[1]1tbl.a none . . . . . . . . N . . . . . . . Mn
[1]1zpe.a none . . . . . . . . A . . . . . . . Mn
[1]1zpg.a none . . . . . . . . A . . . . . . . Mn
[1]3e8q.a none . . . . . A . . . . . . . . . . Mn
[1]3e8z.b none . . . . A . . . . . . . . . . . Mn
[1]3e9b.a s2c 13 . . . . . A . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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