ARGI1_HUMAN_1_322

Arginase-1 [Arginase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ARGI1_HUMAN):R: Substrate binding (126,128,130)
R: Substrate binding (137)
101,124,134:136,141,142,181,183,186,232,234,246,277
101,124,126,128,130,134:137,141,142,181,183,186,232,234,246,277
Metals (Me):Co/Mn

Full PDB list

1wva,1wvb,2aeb,2pha,2pho,2pll,2zav,3dj8,3e6k,3e6v,3f80,3gmz,3gn0,3kv2,3lp4,3lp7,3mfv,3mfw,3mjl,3sjt,3skk,3tf3,3th7,3the,3thh,3thj,4fci,4fck,4gsm,4gsv,4gsz,4gwc,4gwd,4hww,4hxq,4ie1 (redundant pocketome entry)

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
H
1
0
1
D
1
2
4
H
1
2
6
D
1
2
8
N
1
3
0
T
1
3
4
T
1
3
5
T
1
3
6
S
1
3
7
H
1
4
1
G
1
4
2
D
1
8
1
D
1
8
3
E
1
8
6
D
2
3
2
D
2
3
4
T
2
4
6
E
2
7
7
[1]3gn0.a dmo 12 . . . . . . . . . . . . . . . . . . Mn
[1]3the.b bcn 11 . . . . . . . . . . . . . . . . . . Co
[1]4fci.a gpa 10 . . . . . . . . . . . . . . . . . . Mn
[1]1wva.a s2c 13 . . . . . . . . . . . . . . . . . . Mn
[1]3dj8.a exy 12 . . . . . . . . . . . . . . . . . . Mn
[1]3e6k.a abh 13 . . . . . . . . . . . . A . . . . . Mn
[1]3e6v.b abh 13 . . . . . . . . . . . . N . . . . . Mn
[1]3f80.a 6hn 12 . . . . . . . . . . . . . . . . . . Mn
[1]3gmz.b orn 9 . . . . . . . . . . . . . . . . . . Mn
[1]3kv2.a nnh 12 . . . . . . . . . . . . . . . . . . Mn
[1]3lp4.a K 10 . . . . . . . . . . . . . . . . . . Mn
[1]3lp7.a har 13 . . . . . . . . . . . . . . . . . . Mn
[1]3mfv.a z70 13 . . . . . . . . . . . . . . . . . . Mn
[1]3mfw.a b3u 12 . . . . . . . . . . . . . . . . . . Mn
[1]3mjl.a 2ai 6 . . . . . . . . . . . . . . . . . . Mn
[1]3sjt.a 5ab 14 . . . . . . . . . . . . . . . . . . Mn
[1]3skk.a 4u7 16 . . . . . . . . . . . . . . . . . . Mn
[1]3tf3.b none . . . . . . . . . . . . . . . . . .
[1]3thh.a abh 13 . . . . . . . . . . . . . . . . . . Co
[1]3thj.a orn-orn 18 . . . . . . . . . . . . . . . . . . Co
[1]4gwc.a zn 1 . . . . . . . . . . . . . . . . . . Mn
[1]4gwd.a abh,zn 14 . . . . . . . . . . . . . . . . . . Mn
[1]4hww.a x7a 21 . . . . . . . . . . . . . . . . . . Mn
[1]4hxq.a x8a 22 . . . . . . . . . . . . . . . . . . Mn
[1]4ie1.a 1ec 17 . . . . . . . . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback