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ARGI1_HUMAN_1_322

Arginase-1 [Arginase family]

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (ARGI1_HUMAN):R: Substrate binding (126, 128, 130)
R: Substrate binding (137)
66, 101, 124, 133:136, 141, 142, 181, 183, 185, 186, 232, 234, 246, 277
66, 101, 124, 126, 128, 130, 133:137, 141, 142, 181, 183, 185, 186, 232, 234, 246, 277
Metals (Me):Co/Mn

Full PDB list

1wva, 1wvb, 2aeb, 2pha, 2pho, 2pll, 2zav, 3dj8, 3e6k, 3e6v, 3f80, 3gmz, 3gn0, 3kv2, 3lp4, 3lp7, 3mfv, 3mfw, 3mjl, 3sjt, 3skk, 3tf3, 3th7, 3the, 3thh, 3thj, 4fci, 4fck, 4gsm, 4gsv, 4gsz, 4gwc, 4gwd, 4hww, 4hxq, 4ie1 (redundant Pocketome entry)

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
H
1
0
1
D
1
2
4
H
1
2
6
D
1
2
8
N
1
3
0
T
1
3
4
T
1
3
5
T
1
3
6
S
1
3
7
H
1
4
1
G
1
4
2
D
1
8
1
D
1
8
3
E
1
8
6
D
2
3
2
D
2
3
4
T
2
4
6
E
2
7
7
[1]1wva.a s2c13 . . . . . . . . . . . . . . . . . . Mn
[1]3dj8.a exy12 . . . . . . . . . . . . . . . . . . Mn
[1]3e6k.b abh13 . . . . . . . . . . . . A . . . . . Mn
[1]3e6v.b abh13 . . . . . . . . . . . . N . . . . . Mn
[1]3f80.a 6hn12 . . . . . . . . . . . . . . . . . . Mn
[1]3gmz.a orn9 . . . . . . . . . . . . . . . . . . Mn
[1]3gn0.a dmo12 . . . . . . . . . . . . . . . . . . Mn
[1]3kv2.a nnh12 . . . . . . . . . . . . . . . . . . Mn
[1]3lp4.a K10 . . . . . . . . . . . . . . . . . . Mn
[1]3lp7.a har13 . . . . . . . . . . . . . . . . . . Mn
[1]3mfv.a z7013 . . . . . . . . . . . . . . . . . . Mn
[1]3mfw.a b3u12 . . . . . . . . . . . . . . . . . . Mn
[1]3mjl.a 2ai6 . . . . . . . . . . . . . . . . . . Mn
[1]3sjt.a 5ab14 . . . . . . . . . . . . . . . . . . Mn
[1]3skk.a 4u716 . . . . . . . . . . . . . . . . . . Mn
[1]3tf3.b none . . . . . . . . . . . . . . . . . .
[1]3the.b bcn11 . . . . . . . . . . . . . . . . . . Co
[1]3thh.a abh13 . . . . . . . . . . . . . . . . . . Co
[1]3thj.a orn-orn18 . . . . . . . . . . . . . . . . . . Co
[1]4fci.a gpa10 . . . . . . . . . . . . . . . . . . Mn
[1]4gwc.a zn1 . . . . . . . . . . . . . . . . . . Mn
[1]4gwd.a abh,zn14 . . . . . . . . . . . . . . . . . . Mn
[1]4hww.a x7a21 . . . . . . . . . . . . . . . . . . Mn
[1]4hxq.a x8a22 . . . . . . . . . . . . . . . . . . Mn
[1]4ie1.a 1ec17 . . . . . . . . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 Me
I
6
6
H
1
0
1
D
1
2
4
H
1
2
6
D
1
2
8
N
1
3
0
L
1
3
3
T
1
3
4
T
1
3
5
T
1
3
6
S
1
3
7
H
1
4
1
G
1
4
2
D
1
8
1
D
1
8
3
G
1
8
5
E
1
8
6
D
2
3
2
D
2
3
4
T
2
4
6
E
2
7
7
[1]1wva.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3dj8.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3e6k.b . . . . . . . . . . . . . . A . . . . . . Mn
[1]3e6v.b . . . . . . . . . . . . . . N . . . . . . Mn
[1]3f80.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3gmz.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3gn0.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3kv2.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3lp4.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3lp7.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3mfv.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3mfw.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3mjl.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3sjt.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3skk.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]3tf3.b . . . . . . . . . . . . . . . . . . . . .
[1]3the.b . . . . . . . . . . . . . . . . . . . . . Co
[1]3thh.a . . . . . . . . . . . . . . . . . . . . . Co
[1]3thj.a . . . . . . . . . . . . . . . . . . . . . Co
[1]4fci.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]4gwc.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]4gwd.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]4hww.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]4hxq.a . . . . . . . . . . . . . . . . . . . . . Mn
[1]4ie1.a . . . . . . . . . . . . . . . . . . . . . Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
1wva.a:s2c
3dj8.a:exy
3e6k.b:abh
3e6v.b:abh
3f80.a:6hn
3gmz.a:orn
3gn0.a:dmo
3kv2.a:nnh
3lp4.a:K
3lp7.a:har
3mfv.a:z70
3mfw.a:b3u
3mjl.a:2ai
3sjt.a:5ab
3skk.a:4u7
3tf3.b is apo
3the.b:bcn
3thh.a:abh
3thj.a:orn-orn
4fci.a:gpa
4gwc.a:zn
4gwd.a:abh,zn
4hww.a:x7a
4hxq.a:x8a
4ie1.a:1ec
[1] 1wva.a
0
0.1 0.1 0.2 0 0 0.1 0.1 0 0.2 0.2 0.2 0 0.1 0 - 0.4 0 0.1 0.4 0.3 0.5 0.1 0.2 0.1
[1] 3dj8.a 0
0.1
0.1 0.2 0 0 0 0.1 0 0.2 0.3 0.3 0.1 0 0 - 0.4 0 0.1 0.2 0.1 0.8 0.1 0.2 0.1
[1] 3e6k.b 0 0
0
0.1 0 0 0 0 0 0.1 0.1 0.1 0.1 0 0 - 0.1 0 0.2 0 0.1 0.3 0 0 0.1
[1] 3e6v.b 0 0.1 0
0.1
0 0 0 0 0.1 0.2 0.2 0.1 0 0 0 - 0.4 0 0.1 0.2 0.2 0.4 0 0.1 0.1
[1] 3f80.a 0.1 0.2 0.1 0.1
0
0.1 0.1 0.2 0.1 0.2 0.4 0.7 0.3 0.1 0.1 - 0.6 0.1 0.2 0.5 0.1 0.9 0.1 0.2 0.3
[1] 3gmz.a 0 0.2 0.1 0.1 0
0
0.1 0.2 0.1 0.3 0.3 0.4 0.3 0 0 - 0.4 0 0.2 0.6 0.3 0.9 0.1 0.1 0.2
[1] 3gn0.a 0.1 0.2 0.1 0.1 0 0.1
0.1
0.2 0.1 0.2 0.5 0.8 0.3 0.1 0.1 - 0.6 0.1 0.3 0.6 0.3 1.1 0.2 0.1 0.2
[1] 3kv2.a 0.1 0.2 0.1 0.1 0 0.1 0.1
0.1
0.1 0.2 0.3 0.3 0.1 0.1 0.1 - 0.5 0.1 0.3 0.6 0.1 0.9 0.1 0.1 0.2
[1] 3lp4.a 0 0.1 0.1 0.1 0.1 0 0.1 0.2
0
0.2 0.3 0.3 0.2 0.1 0 - 0.4 0.1 0.2 0.3 0.1 0.9 0.1 0.1 0.1
[1] 3lp7.a 0 0.1 0.1 0.1 0 0.1 0.1 0.2 0
0.2
0.3 0.3 0.1 0.1 0 - 0.4 0.1 0.2 0.3 0.1 0.7 0.1 0.1 0.1
[1] 3mfv.a 0 0.1 0 0.1 0 0 0 0.1 0.1 0.2
0.2
0.3 0 0 0 - 0.3 0 0.2 0.2 0.3 0.8 0 0.1 0.1
[1] 3mfw.a 0 0 0 0.1 0 0 0 0 0.1 0.2 0.2
0.1
0 0 0 - 0.2 0 0.2 0.2 0.1 1.0 0 0.1 0
[1] 3mjl.a 0.1 0 0 0 0 0 0 0.1 0.1 0.2 0.2 0.1
0
0 0 - 0.2 0 0.1 0 0.3 0.9 0 0 0
[1] 3sjt.a 0 0.1 0.1 0.1 0 0 0.1 0 0.2 0.2 0.2 0.2 0
0
0 - 0.5 0 0.1 0.5 0.1 0.9 0.1 0.1 0.1
[1] 3skk.a 0 0.2 0.1 0.1 0 0.1 0.1 0.1 0 0.2 0.2 0.2 0 0.1
0
- 0.4 0.1 0.2 0.3 0.1 0.7 0.1 0.1 0.1
[1] 3tf3.b 0 0 0 0.1 0 0 0 0.1 0.1 0 0.1 0.1 0.1 0 0
-
0.1 0 0.1 0.2 0.1 0.7 0 0.1 0
[1] 3the.b 0.2 0.1 0 0 0 0 0 0.2 0.2 0.2 0.4 0.2 0.1 0 0 -
0.1
0 0.1 0.1 0.4 0.7 0 0 0
[1] 3thh.a 0 0.2 0.1 0.1 0 0 0.1 0.1 0.1 0.2 0.2 0.3 0.1 0 0 - 0.4
0
0.1 0.6 0.1 0.7 0.1 0.1 0.1
[1] 3thj.a 0 0.1 0.1 0.1 0 0.1 0.1 0.2 0.1 0.3 0.3 0.5 0.3 0.1 0 - 0.5 0.1
0.3
0.4 0.3 0.8 0.1 0.1 0.1
[1] 4fci.a 0 0 0 0.1 0 0 0 0.1 0.1 0.1 0.3 0.3 0 0 0 - 0.4 0 0.2
0.2
0.3 0.8 0 0.1 0.1
[1] 4gwc.a 0 0 0 0 0 0 0 0.1 0.1 0.1 0.1 0.1 0.1 0 0 - 0.1 0 0.1 0
0.1
0.8 0 0 0
[1] 4gwd.a 0 0 0 0.1 0 0 0 0.1 0.1 0.2 0.3 0.3 0.3 0 0 - 0.1 0 0.2 0.1 0.4
0.5
0 0.1 0
[1] 4hww.a 0 0 0 0.1 0 0 0 0.1 0.1 0.2 0.3 0.3 0.1 0 0 - 0.3 0 0.2 0.2 0.1 0.8
0
0.1 0
[1] 4hxq.a 0 0 0 0.1 0 0 0 0.1 0.1 0.2 0.2 0.3 0 0 0 - 0.1 0 0.2 0.2 0.1 0.8 0
0.1
0
[1] 4ie1.a 0 0.1 0.1 0.2 0 0.1 0.1 0.1 0.1 0.2 0.3 0.4 0.1 0.1 0 - 0.4 0.1 0.2 0.3 0.1 0.8 0.1 0.1
0.1
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
1wva.a
3dj8.a
3e6k.b
3e6v.b
3f80.a
3gmz.a
3gn0.a
3kv2.a
3lp4.a
3lp7.a
3mfv.a
3mfw.a
3mjl.a
3sjt.a
3skk.a
3tf3.b
3the.b
3thh.a
3thj.a
4fci.a
4gwc.a
4gwd.a
4hww.a
4hxq.a
4ie1.a
[1] 1wva.a
0
.03 .04 .01 .04 .04 .05 .03 .03 .02 .02 .03 .05 .02 .01 .03 .03 .03 .03 .02 .04 .04 .02 .03 .02
[1] 3dj8.a .03
0
.04 .03 .05 .05 .04 .04 .01 .02 .03 .03 .04 .04 .03 .04 .04 .03 .04 .02 .04 .05 .04 .05 .03
[1] 3e6k.b .04 .04
0
.04 .06 .06 .07 .05 .05 .04 .03 .04 .04 .06 .05 .03 .03 .05 .05 .03 .03 .03 .03 .03 .05
[1] 3e6v.b .01 .03 .04
0
.05 .05 .06 .04 .04 .03 .03 .04 .05 .03 .02 .04 .03 .02 .04 .04 .04 .05 .03 .04 .03
[1] 3f80.a .04 .05 .06 .05
0
0 .01 .01 .04 .03 .03 .05 .05 .03 .03 .05 .05 .03 .01 .03 .05 .04 .03 .03 .02
[1] 3gmz.a .04 .05 .06 .05 0
0
.01 .01 .04 .03 .03 .05 .06 .02 .03 .05 .05 .03 .01 .02 .06 .03 .03 .03 .02
[1] 3gn0.a .05 .04 .07 .06 .01 .01
0
.02 .03 .04 .04 .04 .05 .03 .04 .06 .06 .04 .02 .03 .06 .04 .04 .04 .03
[1] 3kv2.a .03 .04 .05 .04 .01 .01 .02
0
.04 .02 .02 .04 .05 .01 .02 .04 .04 .02 .02 .01 .05 .04 .02 .03 .02
[1] 3lp4.a .03 .01 .05 .04 .04 .04 .03 .04
0
.02 .03 .03 .04 .04 .03 .04 .04 .04 .03 .02 .04 .04 .04 .04 .02
[1] 3lp7.a .02 .02 .04 .03 .03 .03 .04 .02 .02
0
.01 .03 .04 .02 .01 .02 .02 .03 .02 0 .03 .03 .02 .03 .01
[1] 3mfv.a .02 .03 .03 .03 .03 .03 .04 .02 .03 .01
0
.02 .03 .03 .02 .02 .02 .04 .02 0 .03 .02 .01 .02 .02
[1] 3mfw.a .03 .03 .04 .04 .05 .05 .04 .04 .03 .03 .02
0
.02 .04 .03 .03 .03 .06 .04 .02 .03 .03 .02 .03 .04
[1] 3mjl.a .05 .04 .04 .05 .05 .06 .05 .05 .04 .04 .03 .02
0
.06 .04 .04 .04 .07 .05 .03 .02 .04 .03 .04 .05
[1] 3sjt.a .02 .04 .06 .03 .03 .02 .03 .01 .04 .02 .03 .04 .06
0
.02 .04 .03 .01 .03 .03 .05 .05 .03 .04 .02
[1] 3skk.a .01 .03 .05 .02 .03 .03 .04 .02 .03 .01 .02 .03 .04 .02
0
.03 .03 .03 .02 .02 .03 .05 .02 .03 .01
[1] 3tf3.b .03 .04 .03 .04 .05 .05 .06 .04 .04 .02 .02 .03 .04 .04 .03
0
.01 .05 .04 .02 .02 .02 .02 .02 .03
[1] 3the.b .03 .04 .03 .03 .05 .05 .06 .04 .04 .02 .02 .03 .04 .03 .03 .01
0
.04 .04 .02 .02 .01 .02 .02 .03
[1] 3thh.a .03 .03 .05 .02 .03 .03 .04 .02 .04 .03 .04 .06 .07 .01 .03 .05 .04
0
.04 .03 .06 .05 .04 .05 .03
[1] 3thj.a .03 .04 .05 .04 .01 .01 .02 .02 .03 .02 .02 .04 .05 .03 .02 .04 .04 .04
0
.01 .05 .02 .02 .02 .01
[1] 4fci.a .02 .02 .03 .04 .03 .02 .03 .01 .02 0 0 .02 .03 .03 .02 .02 .02 .03 .01
0
.03 .03 .01 .02 .01
[1] 4gwc.a .04 .04 .03 .04 .05 .06 .06 .05 .04 .03 .03 .03 .02 .05 .03 .02 .02 .06 .05 .03
0
.03 .03 .03 .04
[1] 4gwd.a .04 .05 .03 .05 .04 .03 .04 .04 .04 .03 .02 .03 .04 .05 .05 .02 .01 .05 .02 .03 .03
0
.02 .01 .03
[1] 4hww.a .02 .04 .03 .03 .03 .03 .04 .02 .04 .02 .01 .02 .03 .03 .02 .02 .02 .04 .02 .01 .03 .02
0
.01 .02
[1] 4hxq.a .03 .05 .03 .04 .03 .03 .04 .03 .04 .03 .02 .03 .04 .04 .03 .02 .02 .05 .02 .02 .03 .01 .01
0
.02
[1] 4ie1.a .02 .03 .05 .03 .02 .02 .03 .02 .02 .01 .02 .04 .05 .02 .01 .03 .03 .03 .01 .01 .04 .03 .02 .02
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 0.5 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1wva.a
3dj8.a
3e6k.b
3e6v.b
3f80.a
3gmz.a
3gn0.a
3kv2.a
3lp4.a
3lp7.a
3mfv.a
3mfw.a
3mjl.a
3sjt.a
3skk.a
3tf3.b
3the.b
3thh.a
3thj.a
4fci.a
4gwc.a
4gwd.a
4hww.a
4hxq.a
4ie1.a
[1] 1wva.a
0
0.2 0.3 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.3 0.3 0.3 0.2 0.2 0.2 0.3 0.3 0.2 0.3 0.2
[1] 3dj8.a 0.2
0
0.3 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.1
[1] 3e6k.b 0.3 0.3
0
0.3 0.4 0.3 0.4 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.4 0.4 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.3
[1] 3e6v.b 0.3 0.2 0.3
0
0.2 0.2 0.3 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.2 0.3 0.4 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.2
[1] 3f80.a 0.3 0.1 0.4 0.2
0
0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.4 0.2 0.1 0.2 0.4 0.2 0.1 0.2 0.2
[1] 3gmz.a 0.2 0.1 0.3 0.2 0.1
0
0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1
[1] 3gn0.a 0.3 0.2 0.4 0.3 0.1 0.1
0
0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.2
[1] 3kv2.a 0.2 0.1 0.3 0.2 0.1 0.1 0.2
0
0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.4 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.2
[1] 3lp4.a 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.2
0
0.2 0.1 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2
[1] 3lp7.a 0.2 0.1 0.4 0.3 0.2 0.2 0.2 0.2 0.2
0
0.1 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.2
[1] 3mfv.a 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1
0
0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.2
[1] 3mfw.a 0.3 0.2 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2
0
0.2 0.2 0.2 0.3 0.4 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.2
[1] 3mjl.a 0.3 0.2 0.4 0.3 0.2 0.2 0.3 0.2 0.2 0.2 0.2 0.2
0
0.2 0.2 0.3 0.4 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.2
[1] 3sjt.a 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2
0
0.2 0.3 0.3 0.2 0.2 0.2 0.4 0.2 0.1 0.2 0.1
[1] 3skk.a 0.3 0.1 0.4 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2
0
0.3 0.3 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.2
[1] 3tf3.b 0.3 0.2 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.2 0.2 0.3 0.3 0.3 0.3
0
0.4 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.3
[1] 3the.b 0.3 0.3 0.4 0.4 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.4
0
0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.3
[1] 3thh.a 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.3
0
0.2 0.2 0.3 0.2 0.2 0.2 0.2
[1] 3thj.a 0.2 0.1 0.4 0.2 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.4 0.2
0
0.2 0.4 0.2 0.2 0.2 0.2
[1] 4fci.a 0.2 0.1 0.3 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.2
0
0.3 0.2 0.1 0.2 0.1
[1] 4gwc.a 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.3 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.3 0.4 0.3
0
0.3 0.4 0.4 0.4
[1] 4gwd.a 0.3 0.1 0.4 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.3
0
0.2 0.2 0.2
[1] 4hww.a 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.4 0.2
0
0.1 0.1
[1] 4hxq.a 0.3 0.2 0.4 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.4 0.2 0.1
0
0.2
[1] 4ie1.a 0.2 0.1 0.3 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 0.2 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1wva.a
3dj8.a
3e6k.b
3e6v.b
3f80.a
3gmz.a
3gn0.a
3kv2.a
3lp4.a
3lp7.a
3mfv.a
3mfw.a
3mjl.a
3sjt.a
3skk.a
3tf3.b
3the.b
3thh.a
3thj.a
4fci.a
4gwc.a
4gwd.a
4hww.a
4hxq.a
4ie1.a
[1] 1wva.a
0
0.5 0.5 0.5 0.6 0.6 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.4 0.5 0.6 0.5 0.5 0.5 0.6 0.7 0.5 0.6 0.6 0.6
[1] 3dj8.a 0.5
0
0.8 0.4 0.3 0.5 0.5 0.3 0.2 0.3 0.4 0.5 0.4 0.4 0.4 0.5 0.4 0.3 0.3 0.7 0.8 0.5 0.6 0.6 0.6
[1] 3e6k.b 0.5 0.8
0
0.7 0.7 0.6 0.6 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.6 0.7 0.7 0.7 0.7 0.5 0.7 0.6 0.7 0.7 0.7
[1] 3e6v.b 0.5 0.4 0.7
0
0.5 0.6 0.6 0.5 0.4 0.5 0.5 0.6 0.5 0.4 0.4 0.5 0.5 0.3 0.5 0.7 0.8 0.6 0.7 0.7 0.7
[1] 3f80.a 0.6 0.3 0.7 0.5
0
0.5 0.5 0.3 0.4 0.2 0.4 0.5 0.4 0.4 0.5 0.5 0.5 0.4 0.3 0.7 0.8 0.5 0.6 0.6 0.7
[1] 3gmz.a 0.6 0.5 0.6 0.6 0.5
0
0.1 0.5 0.5 0.6 0.4 0.3 0.4 0.5 0.6 0.6 0.6 0.6 0.4 0.4 0.7 0.6 0.6 0.6 0.6
[1] 3gn0.a 0.6 0.5 0.6 0.6 0.5 0.1
0
0.5 0.5 0.6 0.4 0.3 0.4 0.5 0.6 0.6 0.6 0.6 0.4 0.5 0.7 0.6 0.6 0.6 0.6
[1] 3kv2.a 0.5 0.3 0.7 0.5 0.3 0.5 0.5
0
0.4 0.4 0.3 0.4 0.3 0.3 0.5 0.5 0.5 0.5 0.3 0.6 0.8 0.5 0.5 0.6 0.6
[1] 3lp4.a 0.5 0.2 0.7 0.4 0.4 0.5 0.5 0.4
0
0.3 0.4 0.5 0.4 0.4 0.5 0.5 0.4 0.3 0.4 0.7 0.8 0.5 0.6 0.6 0.7
[1] 3lp7.a 0.5 0.3 0.7 0.5 0.2 0.6 0.6 0.4 0.3
0
0.3 0.5 0.4 0.4 0.5 0.5 0.5 0.4 0.4 0.7 0.7 0.5 0.6 0.6 0.7
[1] 3mfv.a 0.5 0.4 0.7 0.5 0.4 0.4 0.4 0.3 0.4 0.3
0
0.3 0.2 0.4 0.5 0.5 0.4 0.4 0.2 0.6 0.7 0.4 0.6 0.6 0.6
[1] 3mfw.a 0.5 0.5 0.6 0.6 0.5 0.3 0.3 0.4 0.5 0.5 0.3
0
0.3 0.5 0.6 0.6 0.6 0.5 0.3 0.5 0.7 0.5 0.6 0.6 0.6
[1] 3mjl.a 0.5 0.4 0.7 0.5 0.4 0.4 0.4 0.3 0.4 0.4 0.2 0.3
0
0.4 0.5 0.5 0.5 0.5 0.3 0.6 0.7 0.4 0.6 0.6 0.6
[1] 3sjt.a 0.4 0.4 0.7 0.4 0.4 0.5 0.5 0.3 0.4 0.4 0.4 0.5 0.4
0
0.4 0.6 0.5 0.3 0.4 0.7 0.8 0.5 0.6 0.6 0.7
[1] 3skk.a 0.5 0.4 0.6 0.4 0.5 0.6 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.4
0
0.5 0.5 0.3 0.5 0.6 0.8 0.5 0.6 0.6 0.7
[1] 3tf3.b 0.6 0.5 0.7 0.5 0.5 0.6 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.6 0.5
0
0.4 0.5 0.5 0.7 0.8 0.6 0.8 0.7 0.8
[1] 3the.b 0.5 0.4 0.7 0.5 0.5 0.6 0.6 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.5 0.4
0
0.4 0.4 0.7 0.8 0.5 0.7 0.7 0.7
[1] 3thh.a 0.5 0.3 0.7 0.3 0.4 0.6 0.6 0.5 0.3 0.4 0.4 0.5 0.5 0.3 0.3 0.5 0.4
0
0.4 0.7 0.8 0.6 0.7 0.7 0.7
[1] 3thj.a 0.5 0.3 0.7 0.5 0.3 0.4 0.4 0.3 0.4 0.4 0.2 0.3 0.3 0.4 0.5 0.5 0.4 0.4
0
0.6 0.8 0.4 0.6 0.6 0.6
[1] 4fci.a 0.6 0.7 0.5 0.7 0.7 0.4 0.5 0.6 0.7 0.7 0.6 0.5 0.6 0.7 0.6 0.7 0.7 0.7 0.6
0
0.4 0.5 0.5 0.5 0.5
[1] 4gwc.a 0.7 0.8 0.7 0.8 0.8 0.7 0.7 0.8 0.8 0.7 0.7 0.7 0.7 0.8 0.8 0.8 0.8 0.8 0.8 0.4
0
0.6 0.7 0.7 0.7
[1] 4gwd.a 0.5 0.5 0.6 0.6 0.5 0.6 0.6 0.5 0.5 0.5 0.4 0.5 0.4 0.5 0.5 0.6 0.5 0.6 0.4 0.5 0.6
0
0.5 0.5 0.6
[1] 4hww.a 0.6 0.6 0.7 0.7 0.6 0.6 0.6 0.5 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.8 0.7 0.7 0.6 0.5 0.7 0.5
0
0.2 0.2
[1] 4hxq.a 0.6 0.6 0.7 0.7 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.7 0.7 0.7 0.6 0.5 0.7 0.5 0.2
0
0.2
[1] 4ie1.a 0.6 0.6 0.7 0.7 0.7 0.6 0.6 0.6 0.7 0.7 0.6 0.6 0.6 0.7 0.7 0.8 0.7 0.7 0.6 0.5 0.7 0.6 0.2 0.2
0
[Binding site full-atom RMSD matrix]







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[ENTRY 2D visualization]

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