APT_HUMAN_1_180

Adenine phosphoribosyltransferase [Purine/pyrimidine phosphoribosyltransferase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer
 • A1 (APT_HUMAN):25:27,66,67,88,127:129,131:135,15925:27,66,67,88,127:129,131:135,159
 • A2 (APT_HUMAN):87,9187,91

Full PDB list

1ore,1zn7,1zn8,1zn9,4x44,4x45 (redundant pocketome entry)

Contact map

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ligand
A1 A2
V
2
5
F
2
6
R
2
7
S
6
6
R
6
7
K
8
8
D
1
2
7
D
1
2
8
L
1
2
9
A
1
3
1
T
1
3
2
G
1
3
3
G
1
3
4
T
1
3
5
L
1
5
9
R
8
7
K
9
1
[1]1zn7.a ade,hsx,mg,prp 47 . . . . . . . . . . . . . . . . .
[1]1zn7.b ade,hsx,prp 46 . . . . . . . . . . . . . . . . .
[1]1zn9.b amp 23 . . . . . . . . . . . . . . . . .
[1]4x45.a none . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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