AOC1_HUMAN_21_751

Amiloride-sensitive amine oxidase [copper-containing] [Copper/topaquinone oxidase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (AOC1_HUMAN):R: Substrate binding (371,373,376,380,381)
R: Substrate binding (458:460)
148,184:186,404
148,184:186,371,373,376,380,381,404,458:460
 • A2 (AOC1_HUMAN):435435
Metals (Me):Cu

Full PDB list

3hi7,3hig,3hii,3k5t,3mph (redundant pocketome entry)

Contact map

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ligand
A1 A2 Me
Y
1
4
8
F
1
8
4
T
1
8
5
D
1
8
6
Y
3
7
1
D
3
7
3
W
3
7
6
S
3
8
0
V
3
8
1
Y
4
0
4
V
4
5
8
Y
4
5
9
N
4
6
0
F
4
3
5
[1]3hii.a pnt 25 . . . . . . . . . . . . . . Cu
[1]3hig.a brn 21 . . . . . . . . . . . . . . Cu
[1]3k5t.a none . . . . . . . . . . . . . . Cu
[1]3mph.b none . . . . . . . . . . . . . . Cu

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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