ANM6_HUMAN_5_375

Protein arginine N-methyltransferase 6 [Class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family. PRMT6 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ANM6_HUMAN):D: SAM-dependent MTase PRMT-type (162,165,168,264,267,268,343:345,350:353)162,165,168,264,267,268,343:345,350:353
Cofactors (cF):sah

Full PDB list

4hc4,4qpp,4qqk,4y2h,4y30,5e8r,5egs,5hzm (redundant pocketome entry)

Contact map

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ligand
A1 cF
L
1
6
2
S
1
6
5
S
1
6
8
E
2
6
4
L
2
6
7
E
2
6
8
L
3
4
3
L
3
4
4
P
3
4
5
P
3
5
0
R
3
5
1
R
3
5
2
L
3
5
3
[1]4qpp.b 36s 26 . . . . . . . . . . . . .
[1]4y30.b none . . . . . Q . . . . . . . sah
[1]4y2h.b none . . . . . . . . . . . . . sah
[1]5egs.c 5nr 16 . . . . . . . . . . . . . sah

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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