AK1C2_HUMAN_1_323

Aldo-keto reductase family 1 member C2 [Aldo/keto reductase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (AK1C2_HUMAN):24,54,55,86,117,118,128,129,216,222,227,306,308,31124,54,55,86,117,118,128,129,216,222,227,306,308,311
Cofactors (cF):nap

Full PDB list

1ihi,1j96,1xjb,2hdj,2ipj,4jq1,4jq2,4jq3,4jq4,4jqa,4jtq,4jtr,4l1w,4l1x,4xo6,4xo7 (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1 cF
Y
2
4
V
5
4
Y
5
5
W
8
6
H
1
1
7
F
1
1
8
V
1
2
8
I
1
2
9
Y
2
1
6
H
2
2
2
W
2
2
7
L
3
0
6
L
3
0
8
F
3
1
1
[1]1ihi.a iu5 28 . . . . . . . . . . . . . . nap
[1]4jq4.a imn 25 . . . . . . . . . . . . . . nap
[1]4jq2.a suz 25 . . . . . . . . . . . . . . nap
[1]4jq3.a zom 20 . . . . . . . . . . . . . . nap
[1]4l1w.a str 23 . . . . . . . . . . . . . . nap
[1]4xo6.a 5sd 21 . . . . . . . . . . . . . . nap
[1]4xo6.b aox 21 . . . . . . . . . . . . . . nap
[1]4xo7.a asd 21 . . . . . . . . . . . . . . nap
[1]1j96.b tes 21 . . . . . . . . . . . . . . nap
[1]4jtq.a flp 18 . . . . . . . . . . . . . . nap
[1]4jqa.a id8 18 . . . . . . . . . . . . . . nap
[1]4jq1.a nps 17 . . . . . . . . . . . . . . nap
[1]4jtr.a ibp 15 . . . . . . . . . . . . . . nap
[1]4jtr.b izp 15 . . . . . . . . . . . . . . nap
[1]1xjb.a none . . . . . . . . . . . . . . nap
[1]4l1x.a str 23 . L . . . . . . . . . . . . nap
[1]2ipj.b ffa 21 A . . . . . . . . . . . . . nap

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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