AGAL_HUMAN_32_429

Alpha-galactosidase A [Glycosyl hydrolase 27 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (AGAL_HUMAN):R: Substrate binding (203,206,207)
47,92,93,134,142,168,170,172,227,230,231
47,92,93,134,142,168,170,172,203,206,207,227,230,231

Full PDB list

1r46,1r47,3gxn,3gxp,3gxt,3hg2,3hg3,3hg4,3hg5,3lx9,3lxa,3lxb,3lxc,3s5y,3s5z,3tv8,4nxs (redundant pocketome entry)

Contact map

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ligand
A1
W
4
7
D
9
2
D
9
3
Y
1
3
4
C
1
4
2
K
1
6
8
D
1
7
0
C
1
7
2
E
2
0
3
L
2
0
6
Y
2
0
7
R
2
2
7
A
2
3
0
D
2
3
1
[1]4nxs.b 2oz 21 . . . . . . . . . . . . . .
[1]3hg4.a 7jz 12 . . . . . . * . . . . . . .
[1]3gxt.a noj 11 . . . . . . . . . . . . . .
[1]1r46.a none . . . . . . . . . . . . . .
[1]3s5y.a dgj 11 . . . . . . . . . . . . . .
[1]3tv8.a dgj 11 . . . . . . A . . . . . . .
[1]3hg3.a gla-glc 23 . . . . . . A . . . . . . .
[1]3lx9.a none . . . . . . . . S A . . . .
[1]3lxa.a gla 12 . . . . . . . . S A . . . .
[1]3s5z.a gla 12 . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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