ADCY2_RAT_870_1082

Adenylate cyclase type 2 [Adenylyl cyclase class-4/guanylyl cyclase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer
 • A1 (ADCY2_RAT):889,938,940,945,1018:1022,1024,1025,1028,1029,1065889,938,940,945,1018:1022,1024,1025,1028,1029,1065
Cofactors (cF):fkp/fok
Metals (Me):Ca/Mg/Mn

Full PDB list

1ab8,1azs,1cjk,1cjt,1cju,1cjv,1cs4,1cul,1tl7,1u0h,2gvd,2gvz,3c14,3c15,3c16,3g82,3maa (redundant pocketome entry)

Contact map

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ligand
A1 cF Me
F
8
8
9
K
9
3
8
I
9
4
0
M
9
4
5
D
1
0
1
8
I
1
0
1
9
W
1
0
2
0
G
1
0
2
1
N
1
0
2
2
V
1
0
2
4
N
1
0
2
5
S
1
0
2
8
R
1
0
2
9
K
1
0
6
5
[1]1cs4.b 101,GF-A-L-D 58 . . . . . . . . . . . . . . fok Mg
[1]1cul.b 103,3po,GF-A-L-D 70 . . . . . . . . . . . . . . fok Mg
[1]1cjt.b dad,GF-A-L-D 65 . . . . . . . . . . . . . . fok Mg,Mn
[1]1ab8.a fok 29 . . . . . . . . . . . . . -
[1]1azs.b none . . . . . . . . . . . . . . fkp
[1]3maa.b tat 31 . . . . . . . . . . . . . . fkp
[1]1cjk.b F-A-D,tat 55 . . . . . . . . . . . . . . fok Mg,Mn
[1]2gvd.b 128 46 . . . . . . . . . . . . . . fkp Mn
[1]2gvz.b ona 41 . . . . . . . . . . . . . . fkp Mn
[1]1u0h.b onm 42 . . . . . . . . . . . . . . fok Mg
[1]3c16.b atp 31 . . . . . . . . . . . . . . fok Ca
[1]3g82.b mi3 41 . . . . . . . . . . . . . . fok Mn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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