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ADA17_HUMAN_215_479

Disintegrin and metalloproteinase domain-containing protein 17

Composition of the binding site

Protein chains monomer [domain annotation]
A1 (ADA17_HUMAN):D: Peptidase M12B (314, 315, 318, 344:356, 389, 390, 394, 398, 401, 402, 405, 406, 409, 414, 415, 432:434, 436:442, 447)314, 315, 318, 344:356, 389, 390, 394, 398, 401, 402, 405, 406, 409, 414, 415, 432:434, 436:442, 447
Metals (Me):Zn

Full PDB list

1bkc, 1zxc, 2a8h, 2ddf, 2fv5, 2fv9, 2i47, 2oi0, 3b92, 3cki, 3e8r, 3edz, 3ewj, 3g42, 3kmc, 3kme, 3l0t, 3l0v, 3le9, 3lea, 3lgp, 3o64

Pocket contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1 Me
V
3
1
4
K
3
1
5
L
3
1
8
M
3
4
5
G
3
4
6
T
3
4
7
L
3
4
8
G
3
4
9
L
3
5
0
A
3
5
1
Y
3
5
2
V
3
5
3
S
3
5
5
N
3
8
9
Y
3
9
0
E
3
9
8
L
4
0
1
V
4
0
2
H
4
0
5
E
4
0
6
H
4
0
9
E
4
1
4
H
4
1
5
K
4
3
2
Y
4
3
3
V
4
3
4
Y
4
3
6
P
4
3
7
I
4
3
8
A
4
3
9
V
4
4
0
S
4
4
1
G
4
4
2
N
4
4
7
[1]1bkc.a inn29 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]1zxc.a ih626 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2a8h.a 4nh27 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2ddf.a inn29 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2fv5.a 54132 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2fv9.b 00232 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2i47.c kgy35 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2oi0.a 28320 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3b92.a 44018 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3cki.a CTCSP-ESLC-LC75 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3e8r.a 615,inn64 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . - - . . Zn
[1]3e8r.b 61535 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3edz.b 55031 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3ewj.b 64235 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3g42.a 79229 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3kmc.b 40322 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3kme.b z5926 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3l0t.b z9417 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3l0v.a 72421 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3le9.a 72726 . . . . . . . . . . . G - . . . . . . . . . . . . . . . . . . . . . Zn
[1]3lea.b z9332 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3lgp.b 50x41 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3o64.b 78638 . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Site contact map

[download in TSV format]
   
PDB.ch
A1 Me
V
3
1
4
K
3
1
5
L
3
1
8
D
3
4
4
M
3
4
5
G
3
4
6
T
3
4
7
L
3
4
8
G
3
4
9
L
3
5
0
A
3
5
1
Y
3
5
2
V
3
5
3
G
3
5
4
S
3
5
5
P
3
5
6
N
3
8
9
Y
3
9
0
I
3
9
4
E
3
9
8
L
4
0
1
V
4
0
2
H
4
0
5
E
4
0
6
H
4
0
9
E
4
1
4
H
4
1
5
K
4
3
2
Y
4
3
3
V
4
3
4
Y
4
3
6
P
4
3
7
I
4
3
8
A
4
3
9
V
4
4
0
S
4
4
1
G
4
4
2
N
4
4
7
[1]1bkc.a . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]1zxc.a . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]2a8h.a . . . . . . . . . . . . . . . . . . . * . . . . . . . . . . . . . * * . . . Zn
[1]2ddf.a . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]2fv5.a . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]2fv9.b . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]2i47.c . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]2oi0.a . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . Zn
[1]3b92.a . * . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3cki.a . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . . Zn
[1]3e8r.a . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . - - . . Zn
[1]3e8r.b . * . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3edz.b . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3ewj.b . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3g42.a . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3kmc.b . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3kme.b . . . . . . . . . . . . G . . . . . . * . . . . . . . . . . . . . . * . . . Zn
[1]3l0t.b . . . . . . . . . . . . G . . . . . . * . . . . . . . . . . . . . . * . . . Zn
[1]3l0v.a . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3le9.a . * . . . . . . . . . . G . - - . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3lea.b . . . . . . . . . . . . G . . . . . . . . . . . . . . . . . . . . . * . . . Zn
[1]3lgp.b . * . . * . . . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . Zn
[1]3o64.b . * . . . . * . . . . . G . . . . . . . . . . . . . . . . . . . . . . . . . Zn

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)

Pocket-ligand steric compatibility

Ligands (x) vs pockets (y) colored by number of steric clashes

zoom: [−] [+]; [view as image]; [download as text]

pocketligand
≥10
9
8
7
6
5
4
3
2
1
0
1bkc.a:inn
1zxc.a:ih6
2a8h.a:4nh
2ddf.a:inn
2fv5.a:541
2fv9.b:002
2i47.c:kgy
2oi0.a:283
3b92.a:440
3cki.a:CTCSP-ESLC-LC
3e8r.a:615,inn
3e8r.b:615
3edz.b:550
3ewj.b:642
3g42.a:792
3kmc.b:403
3kme.b:z59
3l0t.b:z94
3l0v.a:724
3le9.a:727
3lea.b:z93
3lgp.b:50x
3o64.b:786
[1] 1bkc.a
0.1
0.1 0.1 0.1 4.4 0.4 0.3 0.5 0 0.9 4.8 4.8 4.4 4.8 0 0.1 0 0.2 0.1 0 1.6 4.1 3.1
[1] 1zxc.a 0.2
0.1
0.3 0.4 3.7 0.9 0.2 0.2 0 1.2 4.4 4.8 4.4 4.4 0.1 0.1 0.1 0.3 0.5 0.4 0.4 4.2 2.7
[1] 2a8h.a 0.3 0.2
0.3
0.7 4.4 1.3 0.2 0.7 0 1.7 5.6 5.2 4.5 5.1 0.2 0 0.1 0.2 0.3 0.3 0.2 4.4 2.6
[1] 2ddf.a 0.1 0.1 0.3
0.1
4.5 0.7 0 0.3 0 1.2 4.4 4.4 4.1 5.0 0 0 0 0 0.2 0 0.3 3.9 3.2
[1] 2fv5.a 0 0.1 0.2 0
0.1
0.8 0 0 0 1.3 0.3 0.5 0.1 0.3 0.1 0 0 0.1 0.2 0.1 0.1 0.1 0.1
[1] 2fv9.b 0.2 0.1 0.2 0.2 4.0
0
0 0.6 0.2 0.8 4.9 4.6 4.6 4.6 0.2 0.4 0.3 0 0.1 0 0.2 4.7 3.0
[1] 2i47.c 0 0.1 0.3 0.2 3.9 0.7
0.1
0.5 0 1.1 4.3 5.0 4.4 4.5 0.1 0 0.1 0.1 0.4 0.3 0.3 3.9 2.8
[1] 2oi0.a 0 0.1 0.3 0.1 0.1 1.6 1.3
0
0 1.5 1.0 0.9 0.5 1.2 0.1 0.2 0.1 0.2 0.2 0.1 0.7 0.4 0.2
[1] 3b92.a 0.2 0.2 0.3 0.4 3.5 1.0 1.2 0.2
0
1.4 4.6 4.3 4.3 4.3 0.1 0.2 0.2 0.2 0.5 0.3 1.3 3.8 2.7
[1] 3cki.a 0.3 0.3 0.2 0.3 1.4 1.0 0.2 0.6 0.3
0
2.5 2.8 2.2 2.9 0.7 0.2 0.1 0.2 0.7 0.6 0.4 1.9 0.7
[1] 3e8r.a 0.2 0.1 0.1 0.1 0.2 1.0 0 0 0 1.2
0.5
0.3 0.3 0 0 0 0 0 0.1 0 0.1 0.1 0
[1] 3e8r.b 0.7 0.1 0.1 0.9 0.5 1.9 1.1 0.2 0.1 2.6 1.1
0
0.2 0 0 0 0 0 0 0 1.0 0 0
[1] 3edz.b 0.1 0 0 0.1 0.3 0.7 0 0.1 0 0.6 0.4 0.2
0
0.2 0 0 0 0 0 0 0.1 0 0
[1] 3ewj.b 0.2 0 0 0.3 0.4 1.8 0.2 0.3 0 1.3 0.6 0.1 0
0
0 0 0 0 0.1 0 0.2 0 0
[1] 3g42.a 0.1 0.1 0 0.2 4.0 0.6 0.1 0.6 0 0.9 4.6 4.7 4.5 4.4
0
0 0 0 0.1 0.1 0.2 4.4 2.7
[1] 3kmc.b 0.2 0.2 0.3 0.5 4.4 0.9 0.2 1.1 0.1 1.4 4.9 4.6 4.7 4.5 0.2
0
0 0.2 0.3 0.2 0.1 4.6 3.5
[1] 3kme.b 0.8 0.9 1.5 1.6 5.3 3.2 0.8 1.3 0.6 3.3 8.5 6.9 5.8 7.1 0.2 0
0
0.1 0.5 0.3 0.6 5.4 2.6
[1] 3l0t.b 0.1 0.7 1.1 0.2 5.2 2.2 0.8 1.2 0.8 1.0 7.3 7.0 5.3 7.0 0.2 0.1 0.1
0
0 0 0 6.2 3.6
[1] 3l0v.a 0.1 0.3 0.1 0.1 4.6 0.4 0 1.0 0.2 1.4 4.9 4.7 4.7 5.1 0 0 0 0
0
0 0.1 4.6 3.8
[1] 3le9.a 0 0.2 0 0 4.4 0.6 1.0 0.9 0.1 1.0 4.7 4.6 4.6 4.7 0 0 0 0 0
0
1.2 4.1 3.7
[1] 3lea.b 0.1 0.3 0.3 0.4 4.6 0.9 0.3 1.0 0.3 1.6 5.1 5.0 5.2 5.1 0.1 0.1 0 0 0 0.1
0
4.9 3.4
[1] 3lgp.b 2.2 0.5 0.6 2.4 1.1 2.4 1.4 0.2 0.2 4.0 3.0 0.9 1.1 1.3 0.4 0.1 0.1 0.1 0.5 0.5 1.7
0.1
0.1
[1] 3o64.b 1.2 0.5 0.7 1.8 1.0 1.6 1.4 0.2 0.1 4.1 2.6 0.9 1.3 1.1 0.4 0.1 0 0.1 0.5 0.3 1.5 0.1
0
[Pocket-ligand steric clashes matrix]

Pocket clash dissimilarity (1 cluster)

Pockets (x) vs pockets (y) colored by ligand clash profile difference

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥1.
.9
.8
.7
.6
.5
.4
.3
.2
.1
.0
1bkc.a
1zxc.a
2a8h.a
2ddf.a
2fv5.a
2fv9.b
2i47.c
2oi0.a
3b92.a
3cki.a
3e8r.a
3e8r.b
3edz.b
3ewj.b
3g42.a
3kmc.b
3kme.b
3l0t.b
3l0v.a
3le9.a
3lea.b
3lgp.b
3o64.b
[1] 1bkc.a
0
.08 .09 .06 .17 .11 .07 .14 .04 .20 .17 .15 .17 .17 .07 .07 .19 .13 .07 .03 .10 .24 .22
[1] 1zxc.a .08
0
.04 .06 .16 .08 .03 .18 .06 .19 .16 .18 .15 .17 .04 .05 .17 .11 .05 .08 .07 .28 .25
[1] 2a8h.a .09 .04
0
.07 .18 .08 .05 .21 .08 .22 .18 .19 .17 .18 .06 .06 .15 .08 .07 .08 .06 .29 .27
[1] 2ddf.a .06 .06 .07
0
.13 .07 .04 .18 .08 .19 .13 .18 .15 .17 .04 .04 .17 .10 .03 .05 .06 .27 .25
[1] 2fv5.a .17 .16 .18 .13
0
.18 .14 .09 .15 .09 .02 .11 .04 .07 .15 .15 .28 .22 .13 .17 .17 .17 .14
[1] 2fv9.b .11 .08 .08 .07 .18
0
.06 .22 .09 .20 .19 .21 .16 .21 .06 .07 .16 .10 .07 .09 .07 .28 .26
[1] 2i47.c .07 .03 .05 .04 .14 .06
0
.17 .05 .18 .15 .18 .14 .17 .02 .04 .16 .10 .05 .06 .07 .27 .24
[1] 2oi0.a .14 .18 .21 .18 .09 .22 .17
0
.13 .09 .09 .04 .09 .06 .18 .18 .30 .26 .20 .16 .22 .14 .14
[1] 3b92.a .04 .06 .08 .08 .15 .09 .05 .13
0
.19 .16 .13 .15 .17 .06 .07 .19 .13 .08 .05 .11 .23 .21
[1] 3cki.a .20 .19 .22 .19 .09 .20 .18 .09 .19
0
.08 .10 .08 .06 .18 .19 .29 .25 .19 .21 .22 .20 .18
[1] 3e8r.a .17 .16 .18 .13 .02 .19 .15 .09 .16 .08
0
.09 .04 .05 .15 .15 .27 .22 .14 .17 .18 .15 .15
[1] 3e8r.b .15 .18 .19 .18 .11 .21 .18 .04 .13 .10 .09
0
.08 .05 .17 .17 .28 .23 .18 .14 .20 .15 .14
[1] 3edz.b .17 .15 .17 .15 .04 .16 .14 .09 .15 .08 .04 .08
0
.05 .14 .14 .27 .20 .16 .17 .17 .15 .14
[1] 3ewj.b .17 .17 .18 .17 .07 .21 .17 .06 .17 .06 .05 .05 .05
0
.16 .16 .28 .22 .17 .18 .19 .16 .16
[1] 3g42.a .07 .04 .06 .04 .15 .06 .02 .18 .06 .18 .15 .17 .14 .16
0
.04 .16 .09 .04 .05 .06 .26 .24
[1] 3kmc.b .07 .05 .06 .04 .15 .07 .04 .18 .07 .19 .15 .17 .14 .16 .04
0
.15 .10 .05 .06 .05 .25 .22
[1] 3kme.b .19 .17 .15 .17 .28 .16 .16 .30 .19 .29 .27 .28 .27 .28 .16 .15
0
.12 .18 .19 .17 .23 .22
[1] 3l0t.b .13 .11 .08 .10 .22 .10 .10 .26 .13 .25 .22 .23 .20 .22 .09 .10 .12
0
.09 .11 .09 .34 .32
[1] 3l0v.a .07 .05 .07 .03 .13 .07 .05 .20 .08 .19 .14 .18 .16 .17 .04 .05 .18 .09
0
.05 .05 .28 .26
[1] 3le9.a .03 .08 .08 .05 .17 .09 .06 .16 .05 .21 .17 .14 .17 .18 .05 .06 .19 .11 .05
0
.07 .24 .22
[1] 3lea.b .10 .07 .06 .06 .17 .07 .07 .22 .11 .22 .18 .20 .17 .19 .06 .05 .17 .09 .05 .07
0
.28 .25
[1] 3lgp.b .24 .28 .29 .27 .17 .28 .27 .14 .23 .20 .15 .15 .15 .16 .26 .25 .23 .34 .28 .24 .28
0
.05
[1] 3o64.b .22 .25 .27 .25 .14 .26 .24 .14 .21 .18 .15 .14 .14 .16 .24 .22 .22 .32 .26 .22 .25 .05
0
[Pocket clash dissimilarity matrix]

Site backbone RMSD (median 1.4 Å)

Pockets (x) vs pockets (y) colored by RMSD of site residue backbone atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1bkc.a
1zxc.a
2a8h.a
2ddf.a
2fv5.a
2fv9.b
2i47.c
2oi0.a
3b92.a
3cki.a
3e8r.a
3e8r.b
3edz.b
3ewj.b
3g42.a
3kmc.b
3kme.b
3l0t.b
3l0v.a
3le9.a
3lea.b
3lgp.b
3o64.b
[1] 1bkc.a
0
0.4 0.5 3.0 3.8 3.5 0.3 1.2 0.5 0.6 3.0 3.6 3.6 3.6 0.4 3.6 3.6 3.5 2.9 1.0 3.5 3.7 3.7
[1] 1zxc.a 0.4
0
0.3 3.0 3.9 3.6 0.3 1.2 0.4 0.7 3.1 3.7 3.6 3.7 0.2 3.7 3.7 3.6 3.0 1.0 3.6 3.7 3.8
[1] 2a8h.a 0.5 0.3
0
3.1 3.9 3.6 0.4 1.2 0.5 0.8 3.1 3.7 3.7 3.8 0.3 3.7 3.7 3.6 3.0 1.1 3.6 3.8 3.8
[1] 2ddf.a 3.0 3.0 3.1
0
0.7 0.8 3.0 3.2 3.0 3.1 0.3 1.2 1.2 1.2 3.0 0.8 0.9 0.8 0.3 0.2 0.8 1.4 1.2
[1] 2fv5.a 3.8 3.9 3.9 0.7
0
1.3 3.8 3.9 3.7 3.8 0.2 1.3 1.2 1.2 3.9 1.3 1.4 1.3 0.8 0.8 1.4 1.3 1.2
[1] 2fv9.b 3.5 3.6 3.6 0.8 1.3
0
3.6 3.7 3.5 3.6 0.9 1.1 1.0 1.1 3.6 0.6 0.7 0.6 0.9 0.7 0.6 1.1 1.0
[1] 2i47.c 0.3 0.3 0.4 3.0 3.8 3.6
0
1.2 0.4 0.6 3.1 3.7 3.6 3.7 0.3 3.6 3.7 3.6 3.0 1.0 3.6 3.7 3.7
[1] 2oi0.a 1.2 1.2 1.2 3.2 3.9 3.7 1.2
0
1.1 1.1 3.1 3.6 3.6 3.6 1.2 3.8 3.8 3.8 3.2 1.7 3.8 3.7 3.7
[1] 3b92.a 0.5 0.4 0.5 3.0 3.7 3.5 0.4 1.1
0
0.7 3.0 3.6 3.5 3.6 0.4 3.6 3.6 3.5 2.9 1.1 3.5 3.6 3.6
[1] 3cki.a 0.6 0.7 0.8 3.1 3.8 3.6 0.6 1.1 0.7
0
3.1 3.7 3.6 3.7 0.7 3.7 3.7 3.7 3.1 1.2 3.7 3.8 3.8
[1] 3e8r.a 3.0 3.1 3.1 0.3 0.2 0.9 3.1 3.1 3.0 3.1
0
0.9 0.8 0.9 3.1 0.8 1.0 0.8 0.3 0.3 0.8 1.0 1.0
[1] 3e8r.b 3.6 3.7 3.7 1.2 1.3 1.1 3.7 3.6 3.6 3.7 0.9
0
0.6 0.3 3.7 1.1 1.1 1.0 1.3 1.2 1.1 0.7 0.7
[1] 3edz.b 3.6 3.6 3.7 1.2 1.2 1.0 3.6 3.6 3.5 3.6 0.8 0.6
0
0.5 3.6 1.1 1.1 1.0 1.2 1.1 1.1 0.6 0.6
[1] 3ewj.b 3.6 3.7 3.8 1.2 1.2 1.1 3.7 3.6 3.6 3.7 0.9 0.3 0.5
0
3.7 1.1 1.1 1.1 1.3 1.2 1.1 0.8 0.8
[1] 3g42.a 0.4 0.2 0.3 3.0 3.9 3.6 0.3 1.2 0.4 0.7 3.1 3.7 3.6 3.7
0
3.6 3.7 3.6 3.0 1.0 3.6 3.7 3.7
[1] 3kmc.b 3.6 3.7 3.7 0.8 1.3 0.6 3.6 3.8 3.6 3.7 0.8 1.1 1.1 1.1 3.6
0
0.3 0.3 0.8 0.5 0.3 1.1 1.0
[1] 3kme.b 3.6 3.7 3.7 0.9 1.4 0.7 3.7 3.8 3.6 3.7 1.0 1.1 1.1 1.1 3.7 0.3
0
0.5 0.9 0.7 0.4 1.0 0.8
[1] 3l0t.b 3.5 3.6 3.6 0.8 1.3 0.6 3.6 3.8 3.5 3.7 0.8 1.0 1.0 1.1 3.6 0.3 0.5
0
0.8 0.5 0.3 1.1 1.0
[1] 3l0v.a 2.9 3.0 3.0 0.3 0.8 0.9 3.0 3.2 2.9 3.1 0.3 1.3 1.2 1.3 3.0 0.8 0.9 0.8
0
0.1 0.7 1.4 1.3
[1] 3le9.a 1.0 1.0 1.1 0.2 0.8 0.7 1.0 1.7 1.1 1.2 0.3 1.2 1.1 1.2 1.0 0.5 0.7 0.5 0.1
0
0.5 1.3 1.1
[1] 3lea.b 3.5 3.6 3.6 0.8 1.4 0.6 3.6 3.8 3.5 3.7 0.8 1.1 1.1 1.1 3.6 0.3 0.4 0.3 0.7 0.5
0
1.1 1.0
[1] 3lgp.b 3.7 3.7 3.8 1.4 1.3 1.1 3.7 3.7 3.6 3.8 1.0 0.7 0.6 0.8 3.7 1.1 1.0 1.1 1.4 1.3 1.1
0
0.4
[1] 3o64.b 3.7 3.8 3.8 1.2 1.2 1.0 3.7 3.7 3.6 3.8 1.0 0.7 0.6 0.8 3.7 1.0 0.8 1.0 1.3 1.1 1.0 0.4
0
[Binding site backbone RMSD matrix]

Site full-atom RMSD (median 1.2 Å)

Pockets (x) vs pockets (y) colored by RMSD of all site residue atoms

zoom: [−] [+]; [view as image]; [download as text]

pocketpocket
≥10 Å
9 Å
8 Å
7 Å
6 Å
5 Å
4 Å
3 Å
2 Å
1 Å
0 Å
1bkc.a
1zxc.a
2a8h.a
2ddf.a
2fv5.a
2fv9.b
2i47.c
2oi0.a
3b92.a
3cki.a
3e8r.a
3e8r.b
3edz.b
3ewj.b
3g42.a
3kmc.b
3kme.b
3l0t.b
3l0v.a
3le9.a
3lea.b
3lgp.b
3o64.b
[1] 1bkc.a
0
0.9 1.0 2.8 3.4 3.2 0.9 1.3 0.7 1.0 2.9 3.4 3.4 3.4 0.8 3.3 3.4 3.3 2.8 0.9 3.5 3.4 3.4
[1] 1zxc.a 0.9
0
0.5 2.9 3.5 3.3 0.9 1.3 0.8 1.1 2.9 3.6 3.5 3.4 0.6 3.5 3.6 3.5 2.8 1.1 3.8 3.5 3.5
[1] 2a8h.a 1.0 0.5
0
2.9 3.5 3.3 0.8 1.4 0.8 1.1 2.9 3.6 3.5 3.5 0.6 3.5 3.5 3.5 2.9 1.1 3.8 3.5 3.5
[1] 2ddf.a 2.8 2.9 2.9
0
0.8 1.1 2.8 3.0 2.8 2.9 0.3 1.6 1.4 1.5 2.9 1.0 1.2 1.1 0.5 0.6 1.0 1.6 1.4
[1] 2fv5.a 3.4 3.5 3.5 0.8
0
1.5 3.4 3.5 3.4 3.4 0.3 1.5 1.3 1.4 3.5 1.4 1.5 1.5 0.9 1.0 1.5 1.5 1.4
[1] 2fv9.b 3.2 3.3 3.3 1.1 1.5
0
3.2 3.4 3.2 3.3 1.1 1.3 1.1 1.3 3.2 0.7 0.9 0.8 1.1 0.9 0.8 1.3 1.1
[1] 2i47.c 0.9 0.9 0.8 2.8 3.4 3.2
0
1.5 0.9 1.0 2.9 3.5 3.4 3.4 0.7 3.4 3.5 3.4 2.8 1.1 3.6 3.4 3.4
[1] 2oi0.a 1.3 1.3 1.4 3.0 3.5 3.4 1.5
0
1.1 1.3 2.9 3.4 3.4 3.3 1.3 3.6 3.6 3.6 3.0 1.5 3.9 3.4 3.4
[1] 3b92.a 0.7 0.8 0.8 2.8 3.4 3.2 0.9 1.1
0
1.1 2.8 3.4 3.3 3.3 0.8 3.3 3.4 3.3 2.8 1.0 3.6 3.3 3.3
[1] 3cki.a 1.0 1.1 1.1 2.9 3.4 3.3 1.0 1.3 1.1
0
2.9 3.4 3.4 3.4 1.0 3.5 3.5 3.4 2.9 1.2 3.7 3.5 3.5
[1] 3e8r.a 2.9 2.9 2.9 0.3 0.3 1.1 2.9 2.9 2.8 2.9
0
1.1 1.0 1.0 2.9 1.1 1.2 1.1 0.4 0.6 1.0 1.2 1.2
[1] 3e8r.b 3.4 3.6 3.6 1.6 1.5 1.3 3.5 3.4 3.4 3.4 1.1
0
0.8 0.5 3.5 1.3 1.3 1.3 1.6 1.4 1.7 1.0 1.0
[1] 3edz.b 3.4 3.5 3.5 1.4 1.3 1.1 3.4 3.4 3.3 3.4 1.0 0.8
0
0.7 3.5 1.1 1.2 1.1 1.4 1.3 1.6 0.9 0.8
[1] 3ewj.b 3.4 3.4 3.5 1.5 1.4 1.3 3.4 3.3 3.3 3.4 1.0 0.5 0.7
0
3.4 1.2 1.3 1.3 1.5 1.4 1.3 1.0 1.0
[1] 3g42.a 0.8 0.6 0.6 2.9 3.5 3.2 0.7 1.3 0.8 1.0 2.9 3.5 3.5 3.4
0
3.4 3.5 3.4 2.8 1.0 3.7 3.4 3.4
[1] 3kmc.b 3.3 3.5 3.5 1.0 1.4 0.7 3.4 3.6 3.3 3.5 1.1 1.3 1.1 1.2 3.4
0
0.6 0.5 0.9 0.7 1.1 1.3 1.1
[1] 3kme.b 3.4 3.6 3.5 1.2 1.5 0.9 3.5 3.6 3.4 3.5 1.2 1.3 1.2 1.3 3.5 0.6
0
0.6 1.1 0.9 1.3 1.1 1.0
[1] 3l0t.b 3.3 3.5 3.5 1.1 1.5 0.8 3.4 3.6 3.3 3.4 1.1 1.3 1.1 1.3 3.4 0.5 0.6
0
1.0 0.7 1.2 1.3 1.1
[1] 3l0v.a 2.8 2.8 2.9 0.5 0.9 1.1 2.8 3.0 2.8 2.9 0.4 1.6 1.4 1.5 2.8 0.9 1.1 1.0
0
0.5 0.9 1.6 1.4
[1] 3le9.a 0.9 1.1 1.1 0.6 1.0 0.9 1.1 1.5 1.0 1.2 0.6 1.4 1.3 1.4 1.0 0.7 0.9 0.7 0.5
0
0.8 1.4 1.2
[1] 3lea.b 3.5 3.8 3.8 1.0 1.5 0.8 3.6 3.9 3.6 3.7 1.0 1.7 1.6 1.3 3.7 1.1 1.3 1.2 0.9 0.8
0
1.3 1.1
[1] 3lgp.b 3.4 3.5 3.5 1.6 1.5 1.3 3.4 3.4 3.3 3.5 1.2 1.0 0.9 1.0 3.4 1.3 1.1 1.3 1.6 1.4 1.3
0
0.7
[1] 3o64.b 3.4 3.5 3.5 1.4 1.4 1.1 3.4 3.4 3.3 3.5 1.2 1.0 0.8 1.0 3.4 1.1 1.0 1.1 1.4 1.2 1.1 0.7
0
[Binding site full-atom RMSD matrix]







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[ENTRY 2D visualization]

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