ACM2_HUMAN_1_466_TM

Muscarinic acetylcholine receptor M2 [G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ACM2_HUMAN):R: Agonist binding (103,104,107)
R: Agonist binding (403,404)
R: Agonist binding (426,429,430)
108,111,155,181,187,190,191,194,195,400
103,104,107,108,111,155,181,187,190,191,194,195,400,403,404,426,429,430

Full PDB list

3uon,4mqs

Contact map

[download in TSV format]
   
PDB.ch
   
ligand
A1
D
1
0
3
Y
1
0
4
S
1
0
7
N
1
0
8
V
1
1
1
W
1
5
5
F
1
8
1
T
1
8
7
T
1
9
0
A
1
9
1
A
1
9
4
F
1
9
5
W
4
0
0
Y
4
0
3
N
4
0
4
Y
4
2
6
C
4
2
9
Y
4
3
0
[1]3uon.a qnb 25 . . . . . . . . . . . . . . . . . .
[1]4mqs.a ixo 14 . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
Similar entries
Feedback