ACK1_HUMAN_113_392

Activated CDC42 kinase 1 [Protein kinase superfamily. Tyr protein kinase family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ACK1_HUMAN):D: Protein kinase (132:135,137,140,156:158,177,181,190,192,203,205:209,211,212,256,257,259,269:271)132:135,137,140,156:158,177,181,190,192,203,205:209,211,212,256,257,259,269:271

Full PDB list

1u46,1u4d,1u54,3eqp,3eqr,4ewh,4hzr,4hzs,4id7 (redundant pocketome entry)

Contact map

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ligand
A1
L
1
3
2
G
1
3
3
D
1
3
4
G
1
3
5
F
1
3
7
V
1
4
0
A
1
5
6
V
1
5
7
K
1
5
8
E
1
7
7
M
1
8
1
I
1
9
0
L
1
9
2
M
2
0
3
T
2
0
5
E
2
0
6
L
2
0
7
A
2
0
8
P
2
0
9
G
2
1
1
S
2
1
2
R
2
5
6
N
2
5
7
L
2
5
9
G
2
6
9
D
2
7
0
F
2
7
1
[1]4id7.a 1g0 28 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4ewh.b t77 34 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]3eqr.a t74 38 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[2]3eqp.b t95 43 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1u4d.a dbq 18 . . . . . . . . . . . . . . . . . . . . . . . . . . .
[1]1u54.a acp,mg,mg 33 . . . - - . . . . . . . . . . . . . . . . . . . . . .
[1]1u54.b acp,mg 32 . . . - - . . . . . . . . . . . . . . . . . . . . . .
[1]4hzs.a none . . . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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