ACAC_YEAST_1477_2229_inhibitor

Acetyl-CoA carboxylase

ActiveICM:

L C E

Composition of the binding pockets

Protein chains homodimer[show domain annotation]
 • A1 (ACAC_YEAST):R: Carboxyltransferase (1920,1923,1925,1954:1959,1997,1998,2024:2026,2028,2029,2032,2033)
D: CoA carboxyltransferase C-terminal (1920,1923,1925,1954:1959,1997,1998,2024:2026,2028,2029,2032,2033)
1920,1923,1925,1954:1959,1997,1998,2024:2026,2028,2029,2032,2033
 • A2 (ACAC_YEAST):R: Carboxyltransferase (1756,1757,1760:1762,1764:1766)
D: CoA carboxyltransferase N-terminal (1756,1757,1760:1762,1764:1766)
735,1756,1757,1760:1762,1764:1766

Full PDB list

1od2,1od4,1uyr,1uys,1uyt,1uyv,1w2x,3h0j,3h0q,3h0s,3k8x,3pgq,3tv5,3tvu,3tvw,3tz3,4wyo,4wz8,5csk,5csl,5ctb,5ctc,5cte (redundant pocketome entry)

Contact map

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ligand
A1 A2
P
1
9
2
0
V
1
9
2
3
H
1
9
2
5
R
1
9
5
4
G
1
9
5
5
F
1
9
5
6
S
1
9
5
7
G
1
9
5
8
G
1
9
5
9
G
1
9
9
7
G
1
9
9
8
V
2
0
2
4
L
2
0
2
5
E
2
0
2
6
Q
2
0
2
8
G
2
0
2
9
G
2
0
3
2
I
2
0
3
3
K
7
3
5
L
1
7
5
6
T
1
7
5
7
P
1
7
6
0
A
1
7
6
1
I
1
7
6
2
K
1
7
6
4
M
1
7
6
5
L
1
7
6
6
[1]3tvu.a b37 36 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]3tvw.a 07h 30 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]4wyo.c 3w2 30 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]4wz8.c 3w7 29 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]5ctb.a 57j 30 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]5ctc.a 57k 28 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]5cte.b 57l 31 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]3h0s.a b38 28 . . . . . . . . . . . . . . . . . . - . . . . . . . .
[1]3h0j.a b36 34 . . . . . . . . . . . . . . . . . . - . . . . . . . .
[1]3pgq.a none . . . . . . . . . . . . . . . . . . - . . . . . . . .
[1]3h0q.a b37 36 . . . . . . . . . . . . . . . . . . - . . . . . . . .
[1]1w2x.b rcp 36 . . . . . . . . . . . . . . . . . . - . . . . . . . .
[1]5csl.b bti 15 . . . . . . . . . . . . . . . . . . * . . . . . . . .
[1]1od2.a none . . . . . . . . . . . . . . . . . . - . . . . . . * .
[1]3tz3.a none A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]3tz3.b b36 34 A . F . . . . . . . . . . . E . E . - . . S . L . V .
[1]3tv5.c rcp 36 A . F . . . . . . . . . . . E . E . - . . S . L . V .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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