ABL1_HUMAN_61_120_SH3

Tyrosine-protein kinase ABL1 [Protein kinase superfamily. Tyr protein kinase family. ABL subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (ABL1_HUMAN):D: SH3 (70,72,75,77:79,94,98,99,110,112,114,115)70,72,75,77:79,94,98,99,110,112,114,115

Full PDB list

1abo,1abq,1bbz,1opk,1opl,2abl,2fo0,2o88,3eg0,3eg1,3eg2,3eg3,3egu,4j9b,4j9c,4j9d,4j9e,4j9f,4j9g,4j9h,4j9i,4jjb,4jjc,4jjd (redundant pocketome entry)

Contact map

[download in TSV format]
   
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ligand
A1
Y
7
0
F
7
2
S
7
5
D
7
7
N
7
8
T
7
9
N
9
4
E
9
8
W
9
9
W
1
1
0
P
1
1
2
N
1
1
4
Y
1
1
5
[1]1abo.a APTMPPPLPP 71 . . . . . . . . . . . . .
[2]1opk.a none . . . . . . . . . . . . .
[2]2fo0.a none . . . . . . . . . . . . .
[1]1bbz.a aceAPSYSPPPPP 75 . . . . . . . . . . . . .
[1]2o88.a aceAPSYSPPPPP 75 . . . . . . . . . . . A .
[1]3eg0.a none . . . . . . . . . . . T .
[1]3eg1.a aceAPSYSPPPPP 75 . . . . . . . . . . . Q .
[1]3eg2.a none . . . . . . . . . . . Q .
[1]3egu.a none . . . . . . . . . . . A .
[1]4j9c.a aceAPTYSPPLPP 77 . . . . . . . . . . . . .
[1]4j9d.c aceAPTYPPPLPP 78 . . . . . . . . . . . A .
[1]4j9e.c aceAPTYSPPLPP 77 . . . . . . . . . . . A .
[1]4j9f.c aceAPTYPPPLPP 78 . . . . . . . . . . . . .
[1]4j9h.b aceAPTYPPPPPP 77 . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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