AAPK2_HUMAN_2_280_ATPsite

5'-AMP-activated protein kinase catalytic subunit alpha-2 [Protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (AAPK2_HUMAN):D: Protein kinase (22:25,30,43,45,77,93:100,103,104,107,143,144,146,156,157,164)22:25,30,43,45,77,93:100,103,104,107,143,144,146,156,157,164

Full PDB list

2h6d,2yza,3aqv,4cfe,4zhx,5ezv (redundant pocketome entry)

Contact map

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ligand
A1
L
2
2
G
2
3
V
2
4
G
2
5
V
3
0
A
4
3
K
4
5
I
7
7
M
9
3
E
9
4
Y
9
5
V
9
6
S
9
7
G
9
8
G
9
9
E
1
0
0
D
1
0
3
Y
1
0
4
K
1
0
7
E
1
4
3
N
1
4
4
L
1
4
6
A
1
5
6
D
1
5
7
M
1
6
4
[1]3aqv.a tak 30 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]4zhx.a 4o7 35 . . . . . . . . . . . . . . . . . . . . . . . . .
[1]5ezv.a stu 35 . . . . . . . . . . . . . . . . . . . . . . . . .
[2]2h6d.a none . . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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