7OMT8_MEDSA_1_352

Isoflavone-7-O-methyltransferase 8 [Class I-like SAM-binding methyltransferase superfamily. Cation-independent O- methyltransferase family. COMT subfamily]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (7OMT8_MEDSA):R: Substrate binding (118,123,124,127)
142,164,168,254,257,258,310,313
118,123,124,127,142,164,168,254,257,258,310,313

Full PDB list

1fp2,1fpx

Contact map

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ligand
A1
V
1
1
8
L
1
2
3
S
1
2
4
Y
1
2
7
F
1
4
2
F
1
6
4
M
1
6
8
Y
2
5
4
H
2
5
7
N
2
5
8
N
3
1
0
C
3
1
3
[1]1fp2.a hmo 20 . . . . . . . . . . . .
[1]1fpx.a none . . . . . . * . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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