5HT2B_HUMAN_33_405

5-hydroxytryptamine receptor 2B [G-protein coupled receptor 1 family]

ActiveICM:

L C E

Composition of the binding pockets

Protein chains monomer[show domain annotation]
 • A1 (5HT2B_HUMAN):R: Agonist binding (135,136,139,140)
R: Agonist binding (337,340,341)
132,208:211,217,218,221,225,344,347,348,359,362,363,366,370
132,135,136,139,140,208:211,217,218,221,225,337,340,341,344,347,348,359,362,363,366,370

Full PDB list

4ib4,4nc3 (redundant pocketome entry)

Contact map

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ligand
A1
L
1
3
2
D
1
3
5
V
1
3
6
S
1
3
9
T
1
4
0
V
2
0
8
L
2
0
9
T
2
1
0
K
2
1
1
F
2
1
7
M
2
1
8
G
2
2
1
A
2
2
5
W
3
3
7
F
3
4
0
F
3
4
1
N
3
4
4
L
3
4
7
V
3
4
8
Q
3
5
9
L
3
6
2
E
3
6
3
V
3
6
6
Y
3
7
0
[1]4ib4.a erm 43 . . . . . . . . . . . . . . . . . . . . . . . .

Legend

B backbone contact  S side chain contact  F BB + SCh
.
 no contact C covalent bond
X X X X X  clash
X mutation to X * complex cases - deletion
M contact with cofactors/metals (if any)
[icb] Download ICM binary file
[xml] Download XML file
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